The search for better treatments moves forward thanks to a discovery led by the University of California, Irvine.
Researchers at the University of California, Irvine have found out how a certain protein gets turned on in tumour cells.
This could lead to better ways to treat some of the most dangerous types of cancer.
Scientists at the School of Biological Sciences led the research that led to this finding. It could lead to new ways to treat melanoma,
pancreatic adenocarcinoma, the most common type of childhood brain cancer, and adult skin cancer.
The study was written up in the Life Science Alliance journal.
The finding was about the GLI1 protein, which is important for cell growth but has also been linked to a number of cancers.
GLI1 is usually turned on by the Hedgehog signalling pathway, also known as HH.
Scientists have known for almost a decade, though, that HH and the mitogen-activated protein kinase pathway interact in a way that leads to cancer.
This is called "crosstalk. In some cases, proteins in one pathway can turn on proteins in another, said A. Jane Bardwell